MacroMind matchup data: real ranked games, not opinions
Seraphine vs Vayne
What is Seraphine's win rate vs Vayne?
In ADC, Seraphine wins 54% against Vayne across 445 observed ranked games.
Global ranked sample: games from every region and every rank pooled together, not one server's stats. Data runs through patch 26.12; curves updated 2026-08-07.
By 15 minutes the median game has Seraphine ahead by 3 gold.
Seraphine at 15:00
- Gold: +3
- CS: +1
- XP: +334
Typical gap to Vayne, from 445 games that reached 15:00.
Does Seraphine counter Vayne?
Too close to call. Seraphine sits at 54% over 445 games, so neither pick counters the other here. The lane goes to whoever wins the spots below, like the gold lead at 10:00 or staying alive until 15:00, so play for those and let the pick argument go.
How to beat Vayne as Seraphine
When Seraphine is ahead in gold at 10:00, this matchup runs 62% over 213 games; behind, it drops to 47% over 232.
| The spot | Win rate | Games |
|---|---|---|
| Ahead in gold at 10:00 | 62% | 213 |
| Behind in gold at 10:00 | 47% | 232 |
| First blood | 57% | 273 |
| +kills at 10:00 | 66% | 159 |
| +CS at 10:00 | 56% | 209 |
| 0 deaths at 10:00 | 60% | 161 |
| 0 deaths at 15:00 | 66% | 58 |
The median first death in this lane comes at 7:27; the level 6 spike lands around 7:14. Respect the all-in window until your spike is online.
What does Seraphine build in ADC?
Into Vayne specifically, Seraphine finishes Blackfire Torch first most often: 58.4% over 113 games of this matchup.
The most-finished Seraphine core is Blackfire Torch, Archangel's Staff, Rylai's Crystal Scepter: 57.6% across 943 games when all three got done. All matchups, patches 26.1-26.12.
Most games start Doran's Ring + Health Potion + Health Potion; the first finished item is usually Blackfire Torch (4,712 games).
Skill plan: Seraphine players max Q first and take Q at level 1.