MacroMind matchup data: real ranked games, not opinions
Vayne vs Caitlyn
How often does Vayne beat Caitlyn in ADC?
Vayne into Caitlyn in ADC: 50% observed win rate across 6,674 ranked games.
Global ranked sample: games from every region and every rank pooled together, not one server's stats. Data runs through patch 26.12; curves updated 2026-08-07.
By 15 minutes the median game has Vayne behind by 600 gold.
Vayne at 15:00
- Gold: -600
- CS: -17
- XP: -204
Typical gap to Caitlyn, from 6,635 games that reached 15:00.
Does Vayne counter Caitlyn?
No counter here: Vayne sits at 50% over 6,674 games. The swing lives in the spots below, so play the side you know better and chase the row that moves the number the most in this lane, then hold that lead through the first back.
Beating Caitlyn: the Vayne game plan
A gold lead at 10:00 puts Vayne at 63% across 2,349 games. Flip the lead and Vayne falls to 43% across 4,324.
| The spot | Win rate | Games |
|---|---|---|
| Ahead in gold at 10:00 | 63% | 2,349 |
| Behind in gold at 10:00 | 43% | 4,324 |
| First blood | 55% | 3,416 |
| +kills at 10:00 | 60% | 2,686 |
| +CS at 10:00 | 64% | 1,317 |
| 0 deaths at 10:00 | 58% | 1,419 |
| 0 deaths at 15:00 | 64% | 516 |
Someone usually dies here around 5:06 in the median game, and level 6 lands near 7:44. Until your spike is online, respect the all-in.
Vayne's ADC build, with receipts
Into Caitlyn specifically, Vayne finishes Blade of The Ruined King first most often: 50.0% over 1,637 games of this matchup.
The most-finished core in this exact matchup is Blade of The Ruined King, Guinsoo's Rageblade, Terminus: 54.8% across 602 games.
The most-finished Vayne core is Blade of The Ruined King, Guinsoo's Rageblade, Terminus: 56.2% across 7,087 games when all three got done. All matchups, patches 26.1-26.12.
Most games start Doran's Blade + Health Potion; the first finished item is usually Blade of The Ruined King (20,168 games).
Skill plan: Vayne players max Q first and take Q at level 1.