MacroMind matchup data: real ranked games, not opinions
Seraphine vs Cassiopeia
What is Seraphine's win rate vs Cassiopeia?
In Mid, Seraphine wins 52% against Cassiopeia across 27 observed ranked games.
Global ranked sample: games from every region and every rank pooled together, not one server's stats. Data runs through patch 26.12; curves updated 2026-08-07.
By 15 minutes the median game has Seraphine behind by 471 gold.
Seraphine at 15:00
- Gold: -471
- CS: -1
- XP: -240
Typical gap to Cassiopeia, from 27 games that reached 15:00.
How to beat Cassiopeia as Seraphine
The median first death in this lane comes at 7:14; the level 6 spike lands around 5:33. Respect the all-in window until your spike is online.