MacroMind matchup data: real ranked games, not opinions
Cassiopeia vs Seraphine
What is Cassiopeia's win rate vs Seraphine?
In ADC, Cassiopeia wins 53% against Seraphine across 32 observed ranked games.
Global ranked sample: games from every region and every rank pooled together, not one server's stats. Data runs through patch 26.12; curves updated 2026-08-07.
By 15 minutes the median game has Cassiopeia ahead by 159 gold.
Cassiopeia at 15:00
- Gold: +159
- CS: +6
- XP: +77
Typical gap to Seraphine, from 32 games that reached 15:00.
How to beat Seraphine as Cassiopeia
The median first death in this lane comes at 3:07; the level 6 spike lands around 7:12. Respect the all-in window until your spike is online.