MacroMind matchup data: real ranked games, not opinions
Anivia vs Vayne
Anivia vs Vayne in Mid: who wins more often?
Across 28 ranked games in Mid, Anivia beats Vayne in 54% of them.
Global ranked sample: games from every region and every rank pooled together, not one server's stats. Data runs through patch 26.12; curves updated 2026-08-07.
By 15 minutes the median game has Anivia ahead by 436 gold.
Anivia at 15:00
- Gold: +436
- CS: +7
- XP: +860
Typical gap to Vayne, from 28 games that reached 15:00.
Your Anivia game plan against Vayne
In the median game here, the first death comes near 8:49 and level 6 lands around 5:17. Until your spike is online, treat the all-in window with respect.
Anivia in Mid: the items that actually get built
The most-finished Anivia core is Rod of Ages, Archangel's Staff, Liandry's Torment: 55.8% across 3,329 games when all three got done. All matchups, patches 26.1-26.12.
Most games start Doran's Ring + Health Potion + Health Potion; the first finished item is usually Rod of Ages (19,301 games).
Skill plan: Anivia players max E first and take Q at level 1.