MacroMind matchup data: real ranked games, not opinions
Twisted Fate vs Vayne
What is Twisted Fate's win rate vs Vayne?
In ADC, Twisted Fate wins 52% against Vayne across 44 observed ranked games.
Global ranked sample: games from every region and every rank pooled together, not one server's stats. Data runs through patch 26.12; curves updated 2026-08-07.
By 15 minutes the median game has Twisted Fate ahead by 448 gold.
Twisted Fate at 15:00
- Gold: +448
- CS: -3
- XP: -48
Typical gap to Vayne, from 44 games that reached 15:00.
Does Twisted Fate counter Vayne?
Too close to call. Twisted Fate sits at 52% over 44 games, so neither pick counters the other here. The lane goes to whoever wins the spots below, like the gold lead at 10:00 or staying alive until 15:00, so play for those and let the pick argument go.
How to beat Vayne as Twisted Fate
The median first death in this lane comes at 3:57; the level 6 spike lands around 7:26. Respect the all-in window until your spike is online.