MacroMind matchup data: real ranked games, not opinions
Syndra vs Vayne
What is Syndra's win rate vs Vayne?
In Top, Syndra wins 57% against Vayne across 28 observed ranked games.
Global ranked sample: games from every region and every rank pooled together, not one server's stats. Data runs through patch 26.12; curves updated 2026-08-07.
By 15 minutes the median game has Syndra ahead by 465 gold.
Syndra at 15:00
- Gold: +465
- CS: +13
- XP: +574
Typical gap to Vayne, from 28 games that reached 15:00.
How to beat Vayne as Syndra
The median first death in this lane comes at 7:12; the level 6 spike lands around 5:25. Respect the all-in window until your spike is online.