MacroMind matchup data: real ranked games, not opinions
Ryze vs Vayne
Ryze vs Vayne in Mid: who wins more often?
Across 27 ranked games in Mid, Ryze beats Vayne in 48% of them.
Global ranked sample: games from every region and every rank pooled together, not one server's stats. Data runs through patch 26.12; curves updated 2026-08-07.
By 15 minutes the median game has Ryze ahead by 425 gold.
Ryze at 15:00
- Gold: +425
- CS: +12
- XP: +248
Typical gap to Vayne, from 26 games that reached 15:00.
Your Ryze game plan against Vayne
In the median game here, the first death comes near 7:18 and level 6 lands around 5:09. Until your spike is online, treat the all-in window with respect.
Ryze in Mid: the items that actually get built
The most-finished Ryze core is Rod of Ages, Archangel's Staff, Actualizer: 54.9% across 11,436 games when all three got done. All matchups, patches 26.1-26.12.
Most games start Doran's Ring + Health Potion + Health Potion; the first finished item is usually Rod of Ages (24,472 games).
Skill plan: Ryze players max Q first and take E at level 1.