MacroMind matchup data: real ranked games, not opinions
Lissandra vs Ryze
Lissandra vs Ryze in Mid: who wins more often?
Across 926 ranked games in Mid, Lissandra beats Ryze in 54% of them.
Global ranked sample: games from every region and every rank pooled together, not one server's stats. Data runs through patch 26.12; curves updated 2026-08-07.
By 15 minutes the median game has Lissandra ahead by 108 gold.
Lissandra at 15:00
- Gold: +108
- CS: -2
- XP: +30
Typical gap to Ryze, from 920 games that reached 15:00.
Does Lissandra counter Ryze?
On the count, yes. Lissandra takes 54% of 926 ranked Mid games against Ryze. Protect the edge: the rows below show what Lissandra wins with a gold lead at 10:00, and how far it drops from behind, so trade for that lead early and do not give it back.
Your Lissandra game plan against Ryze
With a gold lead at 10:00, Lissandra wins 65% of 456 games in this matchup. Behind at the same mark, the rate drops to 44% over 469.
| The spot | Win rate | Games |
|---|---|---|
| Ahead in gold at 10:00 | 65% | 456 |
| Behind in gold at 10:00 | 44% | 469 |
| First blood | 61% | 466 |
| +kills at 10:00 | 63% | 360 |
| +CS at 10:00 | 64% | 371 |
| 0 deaths at 10:00 | 60% | 320 |
| 0 deaths at 15:00 | 71% | 138 |
In the median game here, the first death comes near 7:02 and level 6 lands around 5:15. Until your spike is online, treat the all-in window with respect.
Lissandra in Mid: the items that actually get built
Into Ryze specifically, Lissandra finishes Malignance first most often: 56.8% over 331 games of this matchup.
The most-finished core in this exact matchup is Malignance, Shadowflame, Zhonya's Hourglass: 58.8% across 68 games.
The most-finished Lissandra core is Malignance, Shadowflame, Zhonya's Hourglass: 55.0% across 4,627 games when all three got done. All matchups, patches 26.1-26.12.
Most games start Doran's Ring + Health Potion + Health Potion; the first finished item is usually Malignance (22,161 games).
Skill plan: Lissandra players max Q first and take Q at level 1.