MacroMind matchup data — real ranked games, not opinions
Ryze vs Lissandra
In Mid, Ryze wins 45% against Lissandra across 643 observed ranked games. This is an observed win rate shown with its sample size, not a prediction or a guaranteed counter.
By 15 minutes the median game has Ryze behind by 83 gold.
Does Ryze counter Lissandra?
No. This one runs the other way: Lissandra takes 55% of 643 ranked Mid games, and the gap clears the noise band.
How to beat Lissandra as Ryze
Turn the early game into gold: 300 up at 10:00 runs this matchup at 57% over 324 games; 300 behind drops it to 32% over 318.
The median first death in this lane comes at 7:06; the level 6 spike lands around 5:11. Respect the all-in window until your spike is online.