MacroMind matchup data — real ranked games, not opinions
Zoe vs Karthus
In Mid, Zoe wins 56% against Karthus across 27 observed ranked games. This is an observed win rate shown with its sample size, not a prediction or a guaranteed counter.
By 15 minutes the median game has Zoe ahead by 278 gold.
How to beat Karthus as Zoe
The median first death in this lane comes at 8:08; the level 6 spike lands around 5:13. Respect the all-in window until your spike is online.