MacroMind matchup data: real ranked games, not opinions

Vayne vs Warwick

What is Vayne's win rate vs Warwick?

In Top, Vayne wins 54% against Warwick across 176 observed ranked games.

Global ranked sample: games from every region and every rank pooled together, not one server's stats. Data runs through patch 26.12; curves updated 2026-08-07.

By 15 minutes the median game has Vayne ahead by 605 gold.

Vayne at 15:00

Typical gap to Warwick, from 174 games that reached 15:00.

Does Vayne counter Warwick?

Too close to call. Vayne sits at 54% over 176 games, so neither pick counters the other here. The lane goes to whoever wins the spots below, like the gold lead at 10:00 or staying alive until 15:00, so play for those and let the pick argument go.

How to beat Warwick as Vayne

When Vayne is ahead in gold at 10:00, this matchup runs 59% over 120 games; behind, it drops to 44% over 55.

The spotWin rateGames
Ahead in gold at 10:0059%120
Behind in gold at 10:0044%55
First blood51%93
+kills at 10:0059%70
+CS at 10:0056%146

The median first death in this lane comes at 4:43; the level 6 spike lands around 5:26. Respect the all-in window until your spike is online.

What does Vayne build in Top?

Into Warwick specifically, Vayne finishes Blade of The Ruined King first most often: 47.8% over 46 games of this matchup.

The most-finished Vayne core is Blade of The Ruined King, Guinsoo's Rageblade, Experimental Hexplate: 58.0% across 1,282 games when all three got done. All matchups, patches 26.1-26.12.

Most games start Doran's Blade + Health Potion; the first finished item is usually Blade of The Ruined King (8,972 games).

Skill plan: Vayne players max Q first and take Q at level 1.

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