MacroMind matchup data: real ranked games, not opinions
Vayne vs Mel
How often does Vayne beat Mel in ADC?
Vayne into Mel in ADC: 57% observed win rate across 651 ranked games.
Global ranked sample: games from every region and every rank pooled together, not one server's stats. Data runs through patch 26.12; curves updated 2026-08-07.
By 15 minutes the median game has Vayne behind by 790 gold.
Vayne at 15:00
- Gold: -790
- CS: -17
- XP: -404
Typical gap to Mel, from 648 games that reached 15:00.
Does Vayne counter Mel?
The count says yes: across 651 ranked ADC games into Mel, Vayne takes 57%. That edge is worth playing for. Check the rows below to see how much a gold lead at 10:00 adds, and what a bad start costs Vayne.
Beating Mel: the Vayne game plan
A gold lead at 10:00 puts Vayne at 68% across 212 games. Flip the lead and Vayne falls to 52% across 439.
| The spot | Win rate | Games |
|---|---|---|
| Ahead in gold at 10:00 | 68% | 212 |
| Behind in gold at 10:00 | 52% | 439 |
| First blood | 60% | 336 |
| +kills at 10:00 | 64% | 202 |
| +CS at 10:00 | 71% | 163 |
| 0 deaths at 10:00 | 60% | 111 |
| 0 deaths at 15:00 | 64% | 42 |
Someone usually dies here around 4:19 in the median game, and level 6 lands near 7:41. Until your spike is online, respect the all-in.
Vayne's ADC build, with receipts
Into Mel specifically, Vayne finishes Blade of The Ruined King first most often: 57.9% over 107 games of this matchup.
The most-finished Vayne core is Blade of The Ruined King, Guinsoo's Rageblade, Terminus: 56.2% across 7,087 games when all three got done. All matchups, patches 26.1-26.12.
Most games start Doran's Blade + Health Potion; the first finished item is usually Blade of The Ruined King (20,168 games).
Skill plan: Vayne players max Q first and take Q at level 1.