MacroMind matchup data: real ranked games, not opinions
Vayne vs Malzahar
What is Vayne's win rate vs Malzahar?
In Mid, Vayne wins 46% against Malzahar across 52 observed ranked games.
Global ranked sample: games from every region and every rank pooled together, not one server's stats. Data runs through patch 26.12; curves updated 2026-08-07.
By 15 minutes the median game has Vayne behind by 238 gold.
Vayne at 15:00
- Gold: -238
- CS: -22
- XP: -457
Typical gap to Malzahar, from 52 games that reached 15:00.
Does Vayne counter Malzahar?
Too close to call. Vayne sits at 46% over 52 games, so neither pick counters the other here. The lane goes to whoever wins the spots below, like the gold lead at 10:00 or staying alive until 15:00, so play for those and let the pick argument go.
How to beat Malzahar as Vayne
The median first death in this lane comes at 7:12; the level 6 spike lands around 5:12. Respect the all-in window until your spike is online.