MacroMind matchup data: real ranked games, not opinions
Vayne vs Dr. Mundo
How often does Vayne beat Dr. Mundo in Top?
Vayne into Dr. Mundo in Top: 53% observed win rate across 847 ranked games.
Global ranked sample: games from every region and every rank pooled together, not one server's stats. Data runs through patch 26.12; curves updated 2026-08-07.
By 15 minutes the median game has Vayne ahead by 280 gold.
Vayne at 15:00
- Gold: +280
- CS: +9
- XP: -67
Typical gap to Dr. Mundo, from 843 games that reached 15:00.
Does Vayne counter Dr. Mundo?
No counter here: Vayne sits at 53% over 847 games. The swing lives in the spots below, so play the side you know better and chase the row that moves the number the most in this lane, then hold that lead through the first back.
Beating Dr. Mundo: the Vayne game plan
A gold lead at 10:00 puts Vayne at 60% across 530 games. Flip the lead and Vayne falls to 41% across 317.
| The spot | Win rate | Games |
|---|---|---|
| Ahead in gold at 10:00 | 60% | 530 |
| Behind in gold at 10:00 | 41% | 317 |
| First blood | 62% | 410 |
| +kills at 10:00 | 60% | 334 |
| +CS at 10:00 | 58% | 599 |
| 0 deaths at 10:00 | 62% | 220 |
| 0 deaths at 15:00 | 63% | 114 |
Someone usually dies here around 5:54 in the median game, and level 6 lands near 5:18. Until your spike is online, respect the all-in.
Vayne's Top build, with receipts
Into Dr. Mundo specifically, Vayne finishes Blade of The Ruined King first most often: 49.8% over 303 games of this matchup.
The most-finished core in this exact matchup is Blade of The Ruined King, Guinsoo's Rageblade, Experimental Hexplate: 58.7% across 63 games.
The most-finished Vayne core is Blade of The Ruined King, Guinsoo's Rageblade, Experimental Hexplate: 58.0% across 1,282 games when all three got done. All matchups, patches 26.1-26.12.
Most games start Doran's Blade + Health Potion; the first finished item is usually Blade of The Ruined King (8,972 games).
Skill plan: Vayne players max Q first and take Q at level 1.