MacroMind matchup data: real ranked games, not opinions
Dr. Mundo vs Vayne
What is Dr. Mundo's win rate vs Vayne?
In Top, Dr. Mundo wins 48% against Vayne across 847 observed ranked games.
Global ranked sample: games from every region and every rank pooled together, not one server's stats. Data runs through patch 26.12; curves updated 2026-08-07.
By 15 minutes the median game has Dr. Mundo behind by 280 gold.
Dr. Mundo at 15:00
- Gold: -280
- CS: -9
- XP: +67
Typical gap to Vayne, from 843 games that reached 15:00.
Does Dr. Mundo counter Vayne?
Too close to call. Dr. Mundo sits at 48% over 847 games, so neither pick counters the other here. The lane goes to whoever wins the spots below, like the gold lead at 10:00 or staying alive until 15:00, so play for those and let the pick argument go.
How to beat Vayne as Dr. Mundo
When Dr. Mundo is ahead in gold at 10:00, this matchup runs 59% over 317 games; behind, it drops to 40% over 530.
| The spot | Win rate | Games |
|---|---|---|
| Ahead in gold at 10:00 | 59% | 317 |
| Behind in gold at 10:00 | 40% | 530 |
| First blood | 57% | 337 |
| +kills at 10:00 | 57% | 258 |
| +CS at 10:00 | 60% | 230 |
| 0 deaths at 10:00 | 52% | 289 |
| 0 deaths at 15:00 | 55% | 137 |
The median first death in this lane comes at 6:34; the level 6 spike lands around 5:26. Respect the all-in window until your spike is online.
What does Dr. Mundo build in Top?
Into Vayne specifically, Dr. Mundo finishes Warmog's Armor first most often: 49.2% over 301 games of this matchup.
The most-finished core in this exact matchup is Warmog's Armor, Heartsteel, Titanic Hydra: 57.6% across 66 games.
The most-finished Dr. Mundo core is Warmog's Armor, Heartsteel, Titanic Hydra: 59.6% across 3,279 games when all three got done. All matchups, patches 26.1-26.12.
Most games start Doran's Shield + Health Potion; the first finished item is usually Warmog's Armor (14,182 games).
Skill plan: Dr. Mundo players max Q first and take Q at level 1.