MacroMind matchup data: real ranked games, not opinions
Seraphine vs Annie
Seraphine vs Annie in Support: who wins more often?
Across 168 ranked games in Support, Seraphine beats Annie in 51% of them.
Global ranked sample: games from every region and every rank pooled together, not one server's stats. Data runs through patch 26.12; curves updated 2026-08-07.
By 15 minutes the median game has Seraphine behind by 79 gold.
Seraphine at 15:00
- Gold: -79
- CS: -1
- XP: +94
Typical gap to Annie, from 166 games that reached 15:00.
Does Seraphine counter Annie?
Even on the count: Seraphine lands at 51% over 168 games. Neither pick wins the lane alone, so take the side you play better and use the rows below to see which early spots swing this one, then play your first ten minutes around them.
Your Seraphine game plan against Annie
With a gold lead at 10:00, Seraphine wins 56% of 81 games in this matchup. Behind at the same mark, the rate drops to 47% over 87.
| The spot | Win rate | Games |
|---|---|---|
| Ahead in gold at 10:00 | 56% | 81 |
| Behind in gold at 10:00 | 47% | 87 |
| First blood | 57% | 69 |
| +kills at 10:00 | 50% | 62 |
| +CS at 10:00 | 48% | 69 |
| 0 deaths at 10:00 | 57% | 44 |
In the median game here, the first death comes near 6:37 and level 6 lands around 8:27. Until your spike is online, treat the all-in window with respect.
Seraphine in Support: the items that actually get built
Into Annie specifically, Seraphine finishes Echoes of Helia first most often: 52.6% over 57 games of this matchup.
The most-finished Seraphine core is Echoes of Helia, Moonstone Renewer, Redemption: 59.4% across 1,196 games when all three got done. All matchups, patches 26.1-26.12.
Most games start Health Potion + Health Potion; the first finished item is usually Echoes of Helia (33,429 games).
Skill plan: Seraphine players max Q first and take Q at level 1.