MacroMind matchup data: real ranked games, not opinions
Miss Fortune vs Vayne
What is Miss Fortune's win rate vs Vayne?
In ADC, Miss Fortune wins 51% against Vayne across 4,447 observed ranked games.
Global ranked sample: games from every region and every rank pooled together, not one server's stats. Data runs through patch 26.12; curves updated 2026-08-07.
By 15 minutes the median game has Miss Fortune ahead by 654 gold.
Miss Fortune at 15:00
- Gold: +654
- CS: +12
- XP: +241
Typical gap to Vayne, from 4,421 games that reached 15:00.
Does Miss Fortune counter Vayne?
Too close to call. Miss Fortune sits at 51% over 4,447 games, so neither pick counters the other here. The lane goes to whoever wins the spots below, like the gold lead at 10:00 or staying alive until 15:00, so play for those and let the pick argument go.
How to beat Vayne as Miss Fortune
When Miss Fortune is ahead in gold at 10:00, this matchup runs 59% over 2,805 games; behind, it drops to 38% over 1,641.
| The spot | Win rate | Games |
|---|---|---|
| Ahead in gold at 10:00 | 59% | 2,805 |
| Behind in gold at 10:00 | 38% | 1,641 |
| First blood | 57% | 2,338 |
| +kills at 10:00 | 62% | 1,755 |
| +CS at 10:00 | 56% | 3,064 |
| 0 deaths at 10:00 | 61% | 963 |
| 0 deaths at 15:00 | 72% | 300 |
The median first death in this lane comes at 5:20; the level 6 spike lands around 7:32. Respect the all-in window until your spike is online.
What does Miss Fortune build in ADC?
Into Vayne specifically, Miss Fortune finishes The Collector first most often: 48.4% over 570 games of this matchup.
The most-finished core in this exact matchup is Hubris, The Collector, Infinity Edge: 56.0% across 225 games.
The most-finished Miss Fortune core is Bloodthirster, The Collector, Infinity Edge: 55.6% across 6,642 games when all three got done. All matchups, patches 26.1-26.12.
Most games start Doran's Blade + Health Potion; the first finished item is usually Bloodthirster (16,018 games).
Skill plan: Miss Fortune players max Q first and take Q at level 1.