MacroMind matchup data: real ranked games, not opinions
Lissandra vs Annie
What is Lissandra's win rate vs Annie?
In Mid, Lissandra wins 48% against Annie across 589 observed ranked games.
Global ranked sample: games from every region and every rank pooled together, not one server's stats. Data runs through patch 26.12; curves updated 2026-08-07.
By 15 minutes the median game has Lissandra ahead by 217 gold.
Lissandra at 15:00
- Gold: +217
- CS: +5
- XP: +162
Typical gap to Annie, from 585 games that reached 15:00.
Does Lissandra counter Annie?
Too close to call. Lissandra sits at 48% over 589 games, so neither pick counters the other here. The lane goes to whoever wins the spots below, like the gold lead at 10:00 or staying alive until 15:00, so play for those and let the pick argument go.
How to beat Annie as Lissandra
When Lissandra is ahead in gold at 10:00, this matchup runs 54% over 327 games; behind, it drops to 41% over 262.
| The spot | Win rate | Games |
|---|---|---|
| Ahead in gold at 10:00 | 54% | 327 |
| Behind in gold at 10:00 | 41% | 262 |
| First blood | 59% | 273 |
| +kills at 10:00 | 57% | 215 |
| +CS at 10:00 | 54% | 330 |
| 0 deaths at 10:00 | 65% | 133 |
| 0 deaths at 15:00 | 77% | 56 |
The median first death in this lane comes at 5:42; the level 6 spike lands around 5:21. Respect the all-in window until your spike is online.
What does Lissandra build in Mid?
Into Annie specifically, Lissandra finishes Malignance first most often: 46.0% over 248 games of this matchup.
The most-finished core in this exact matchup is Malignance, Shadowflame, Zhonya's Hourglass: 68.0% across 50 games.
The most-finished Lissandra core is Malignance, Shadowflame, Zhonya's Hourglass: 55.0% across 4,627 games when all three got done. All matchups, patches 26.1-26.12.
Most games start Doran's Ring + Health Potion + Health Potion; the first finished item is usually Malignance (22,161 games).
Skill plan: Lissandra players max Q first and take Q at level 1.