MacroMind matchup data — real ranked games, not opinions
Cassiopeia vs Annie
What is Cassiopeia's win rate vs Annie?
In Mid, Cassiopeia wins 43% against Annie across 174 observed ranked games. This is an observed win rate shown with its sample size, not a prediction or a guaranteed counter.
By 15 minutes the median game has Cassiopeia ahead by 448 gold.
Does Cassiopeia counter Annie?
No. This one runs the other way: Annie takes 57% of 174 ranked Mid games, and the gap clears the noise band. {{champion}} players still win it — the conditional rates on this page show which spots flip it, each with its own game count.
How to beat Annie as Cassiopeia
When Cassiopeia is 300 gold up at 10:00, this matchup runs 44% over 123 games; 300 down, it drops to 39% over 51.
| The spot | Win rate | Games |
|---|---|---|
| 300 gold up at 10:00 | 44% | 123 |
| 300 gold down at 10:00 | 39% | 51 |
| First blood | 49% | 99 |
| +kills at 10:00 | 51% | 88 |
| +CS at 10:00 | 46% | 127 |
The median first death in this lane comes at 5:42; the level 6 spike lands around 5:18. Respect the all-in window until your spike is online.
What does Cassiopeia build in Mid?
Into Annie specifically, Cassiopeia finishes Rod of Ages first most often: 44.8% over 58 games of this matchup.
The most-finished Cassiopeia core is Rod of Ages, Archangel's Staff, Rylai's Crystal Scepter: 54.2% across 2,129 games when all three got done. All matchups, patches 16.1-16.12.
Most games start Doran's Ring + Health Potion + Health Potion; the first finished item is usually Rod of Ages (5,513 games).
Skill plan: Cassiopeia players max E first and take E at level 1.