MacroMind matchup data: real ranked games, not opinions
Annie vs Cassiopeia
Annie vs Cassiopeia in Mid: who wins more often?
Across 174 ranked games in Mid, Annie beats Cassiopeia in 58% of them.
Global ranked sample: games from every region and every rank pooled together, not one server's stats. Data runs through patch 26.12; curves updated 2026-08-07.
By 15 minutes the median game has Annie behind by 447 gold.
Annie at 15:00
- Gold: -447
- CS: -13
- XP: -407
Typical gap to Cassiopeia, from 174 games that reached 15:00.
Does Annie counter Cassiopeia?
Even on the count: Annie lands at 58% over 174 games. Neither pick wins the lane alone, so take the side you play better and use the rows below to see which early spots swing this one, then play your first ten minutes around them.
Your Annie game plan against Cassiopeia
With a gold lead at 10:00, Annie wins 61% of 51 games in this matchup. Behind at the same mark, the rate drops to 56% over 123.
| The spot | Win rate | Games |
|---|---|---|
| Ahead in gold at 10:00 | 61% | 51 |
| Behind in gold at 10:00 | 56% | 123 |
| First blood | 66% | 73 |
| +kills at 10:00 | 62% | 47 |
| +CS at 10:00 | 68% | 40 |
In the median game here, the first death comes near 5:05 and level 6 lands around 5:36. Until your spike is online, treat the all-in window with respect.
Annie in Mid: the items that actually get built
Into Cassiopeia specifically, Annie finishes Malignance first most often: 56.8% over 74 games of this matchup.
The most-finished Annie core is Malignance, Stormsurge, Shadowflame: 58.6% across 1,865 games when all three got done. All matchups, patches 26.1-26.12.
Most games start Doran's Ring + Health Potion + Health Potion; the first finished item is usually Malignance (12,521 games).
Skill plan: Annie players max Q first and take Q at level 1.