MacroMind matchup data: real ranked games, not opinions
Zoe vs Lissandra
What is Zoe's win rate vs Lissandra?
In Mid, Zoe wins 50% against Lissandra across 881 observed ranked games.
Global ranked sample: games from every region and every rank pooled together, not one server's stats. Data runs through patch 26.12; curves updated 2026-08-07.
By 15 minutes the median game has Zoe ahead by 347 gold.
Zoe at 15:00
- Gold: +347
- CS: +2
- XP: +144
Typical gap to Lissandra, from 877 games that reached 15:00.
Does Zoe counter Lissandra?
Too close to call. Zoe sits at 50% over 881 games, so neither pick counters the other here. The lane goes to whoever wins the spots below, like the gold lead at 10:00 or staying alive until 15:00, so play for those and let the pick argument go.
How to beat Lissandra as Zoe
When Zoe is ahead in gold at 10:00, this matchup runs 55% over 555 games; behind, it drops to 40% over 324.
| The spot | Win rate | Games |
|---|---|---|
| Ahead in gold at 10:00 | 55% | 555 |
| Behind in gold at 10:00 | 40% | 324 |
| First blood | 54% | 586 |
| +kills at 10:00 | 55% | 482 |
| +CS at 10:00 | 55% | 492 |
| 0 deaths at 10:00 | 59% | 235 |
| 0 deaths at 15:00 | 70% | 86 |
The median first death in this lane comes at 6:26; the level 6 spike lands around 5:13. Respect the all-in window until your spike is online.
What does Zoe build in Mid?
Into Lissandra specifically, Zoe finishes Luden's Echo first most often: 49.0% over 433 games of this matchup.
The most-finished core in this exact matchup is Luden's Echo, Shadowflame, Rabadon's Deathcap: 51.1% across 45 games.
The most-finished Zoe core is Luden's Echo, Lich Bane, Shadowflame: 52.4% across 2,086 games when all three got done. All matchups, patches 26.1-26.12.
Most games start Doran's Ring + Health Potion + Health Potion; the first finished item is usually Luden's Echo (22,804 games).
Skill plan: Zoe players max Q first and take Q at level 1.