MacroMind matchup data: real ranked games, not opinions
Zoe vs Cassiopeia
What is Zoe's win rate vs Cassiopeia?
In Mid, Zoe wins 56% against Cassiopeia across 283 observed ranked games.
Global ranked sample: games from every region and every rank pooled together, not one server's stats. Data runs through patch 26.12; curves updated 2026-08-07.
By 15 minutes the median game has Zoe ahead by 367 gold.
Zoe at 15:00
- Gold: +367
- CS: -1
- XP: +223
Typical gap to Cassiopeia, from 281 games that reached 15:00.
Does Zoe counter Cassiopeia?
Too close to call. Zoe sits at 56% over 283 games, so neither pick counters the other here. The lane goes to whoever wins the spots below, like the gold lead at 10:00 or staying alive until 15:00, so play for those and let the pick argument go.
How to beat Cassiopeia as Zoe
When Zoe is ahead in gold at 10:00, this matchup runs 64% over 163 games; behind, it drops to 44% over 120.
| The spot | Win rate | Games |
|---|---|---|
| Ahead in gold at 10:00 | 64% | 163 |
| Behind in gold at 10:00 | 44% | 120 |
| First blood | 62% | 174 |
| +kills at 10:00 | 69% | 142 |
| +CS at 10:00 | 66% | 131 |
| 0 deaths at 10:00 | 64% | 86 |
| 0 deaths at 15:00 | 67% | 46 |
The median first death in this lane comes at 5:33; the level 6 spike lands around 5:27. Respect the all-in window until your spike is online.
What does Zoe build in Mid?
Into Cassiopeia specifically, Zoe finishes Luden's Echo first most often: 52.3% over 109 games of this matchup.
The most-finished Zoe core is Luden's Echo, Lich Bane, Shadowflame: 52.4% across 2,086 games when all three got done. All matchups, patches 26.1-26.12.
Most games start Doran's Ring + Health Potion + Health Potion; the first finished item is usually Luden's Echo (22,804 games).
Skill plan: Zoe players max Q first and take Q at level 1.