MacroMind matchup data: real ranked games, not opinions
Vayne vs Yasuo
What is Vayne's win rate vs Yasuo?
In ADC, Vayne wins 50% against Yasuo across 566 observed ranked games.
Global ranked sample: games from every region and every rank pooled together, not one server's stats. Data runs through patch 26.12; curves updated 2026-08-07.
By 15 minutes the median game has Vayne behind by 483 gold.
Vayne at 15:00
- Gold: -483
- CS: -9
- XP: -251
Typical gap to Yasuo, from 566 games that reached 15:00.
Does Vayne counter Yasuo?
Too close to call. Vayne sits at 50% over 566 games, so neither pick counters the other here. The lane goes to whoever wins the spots below, like the gold lead at 10:00 or staying alive until 15:00, so play for those and let the pick argument go.
How to beat Yasuo as Vayne
When Vayne is ahead in gold at 10:00, this matchup runs 63% over 223 games; behind, it drops to 41% over 343.
| The spot | Win rate | Games |
|---|---|---|
| Ahead in gold at 10:00 | 63% | 223 |
| Behind in gold at 10:00 | 41% | 343 |
| First blood | 53% | 246 |
| +kills at 10:00 | 63% | 186 |
| +CS at 10:00 | 57% | 239 |
| 0 deaths at 10:00 | 59% | 63 |
The median first death in this lane comes at 3:42; the level 6 spike lands around 7:49. Respect the all-in window until your spike is online.
What does Vayne build in ADC?
Into Yasuo specifically, Vayne finishes Blade of The Ruined King first most often: 50.8% over 128 games of this matchup.
The most-finished core in this exact matchup is Blade of The Ruined King, Guinsoo's Rageblade, Terminus: 65.9% across 44 games.
The most-finished Vayne core is Blade of The Ruined King, Guinsoo's Rageblade, Terminus: 56.2% across 7,087 games when all three got done. All matchups, patches 26.1-26.12.
Most games start Doran's Blade + Health Potion; the first finished item is usually Blade of The Ruined King (20,168 games).
Skill plan: Vayne players max Q first and take Q at level 1.