MacroMind matchup data: real ranked games, not opinions
Vayne vs Sett
How often does Vayne beat Sett in Top?
Vayne into Sett in Top: 56% observed win rate across 1,224 ranked games.
Global ranked sample: games from every region and every rank pooled together, not one server's stats. Data runs through patch 26.12; curves updated 2026-08-07.
By 15 minutes the median game has Vayne ahead by 406 gold.
Vayne at 15:00
- Gold: +406
- CS: +20
- XP: +70
Typical gap to Sett, from 1,217 games that reached 15:00.
Does Vayne counter Sett?
The count says yes: across 1,224 ranked Top games into Sett, Vayne takes 56%. That edge is worth playing for. Check the rows below to see how much a gold lead at 10:00 adds, and what a bad start costs Vayne.
Beating Sett: the Vayne game plan
A gold lead at 10:00 puts Vayne at 62% across 715 games. Flip the lead and Vayne falls to 48% across 508.
| The spot | Win rate | Games |
|---|---|---|
| Ahead in gold at 10:00 | 62% | 715 |
| Behind in gold at 10:00 | 48% | 508 |
| First blood | 61% | 491 |
| +kills at 10:00 | 64% | 404 |
| +CS at 10:00 | 59% | 929 |
| 0 deaths at 10:00 | 59% | 192 |
| 0 deaths at 15:00 | 65% | 80 |
Someone usually dies here around 4:26 in the median game, and level 6 lands near 5:31. Until your spike is online, respect the all-in.
Vayne's Top build, with receipts
Into Sett specifically, Vayne finishes Blade of The Ruined King first most often: 57.5% over 341 games of this matchup.
The most-finished core in this exact matchup is Blade of The Ruined King, Guinsoo's Rageblade, Experimental Hexplate: 52.6% across 57 games.
The most-finished Vayne core is Blade of The Ruined King, Guinsoo's Rageblade, Experimental Hexplate: 58.0% across 1,282 games when all three got done. All matchups, patches 26.1-26.12.
Most games start Doran's Blade + Health Potion; the first finished item is usually Blade of The Ruined King (8,972 games).
Skill plan: Vayne players max Q first and take Q at level 1.