MacroMind matchup data: real ranked games, not opinions
Ryze vs Cassiopeia
What is Ryze's win rate vs Cassiopeia?
In Mid, Ryze wins 47% against Cassiopeia across 592 observed ranked games.
Global ranked sample: games from every region and every rank pooled together, not one server's stats. Data runs through patch 26.12; curves updated 2026-08-07.
By 15 minutes the median game has Ryze behind by 206 gold.
Ryze at 15:00
- Gold: -206
- CS: -5
- XP: -181
Typical gap to Cassiopeia, from 587 games that reached 15:00.
Does Ryze counter Cassiopeia?
Too close to call. Ryze sits at 47% over 592 games, so neither pick counters the other here. The lane goes to whoever wins the spots below, like the gold lead at 10:00 or staying alive until 15:00, so play for those and let the pick argument go.
How to beat Cassiopeia as Ryze
When Ryze is ahead in gold at 10:00, this matchup runs 60% over 258 games; behind, it drops to 37% over 334.
| The spot | Win rate | Games |
|---|---|---|
| Ahead in gold at 10:00 | 60% | 258 |
| Behind in gold at 10:00 | 37% | 334 |
| First blood | 54% | 247 |
| +kills at 10:00 | 63% | 163 |
| +CS at 10:00 | 55% | 232 |
| 0 deaths at 10:00 | 53% | 149 |
| 0 deaths at 15:00 | 57% | 65 |
The median first death in this lane comes at 6:00; the level 6 spike lands around 5:28. Respect the all-in window until your spike is online.
What does Ryze build in Mid?
Into Cassiopeia specifically, Ryze finishes Rod of Ages first most often: 50.7% over 288 games of this matchup.
The most-finished core in this exact matchup is Rod of Ages, Archangel's Staff, Actualizer: 57.8% across 147 games.
The most-finished Ryze core is Rod of Ages, Archangel's Staff, Actualizer: 54.9% across 11,436 games when all three got done. All matchups, patches 26.1-26.12.
Most games start Doran's Ring + Health Potion + Health Potion; the first finished item is usually Rod of Ages (24,472 games).
Skill plan: Ryze players max Q first and take E at level 1.