MacroMind matchup data — real ranked games, not opinions
Qiyana vs Karthus
In Jungle, Qiyana wins 42% against Karthus across 293 observed ranked games. This is an observed win rate shown with its sample size, not a prediction or a guaranteed counter.
By 15 minutes the median game has Qiyana behind by 118 gold.
Does Qiyana counter Karthus?
No. This one runs the other way: Karthus takes 58% of 293 ranked Jungle games, and the gap clears the noise band.
How to beat Karthus as Qiyana
Turn the early game into gold: 300 up at 10:00 runs this matchup at 50% over 135 games; 300 behind drops it to 34% over 158.
The median first death in this lane comes at 5:46; the level 6 spike lands around 7:10. Respect the all-in window until your spike is online.