MacroMind matchup data — real ranked games, not opinions
Pantheon vs Karthus
In Jungle, Pantheon wins 51% against Karthus across 133 observed ranked games. This is an observed win rate shown with its sample size, not a prediction or a guaranteed counter.
By 15 minutes the median game has Pantheon behind by 591 gold.
Does Pantheon counter Karthus?
The numbers call it close: 51% for Pantheon over 133 games, inside the noise band. Pick the side you play better.
How to beat Karthus as Pantheon
Turn the early game into gold: 300 up at 10:00 runs this matchup at 61% over 46 games; 300 behind drops it to 45% over 86.
The median first death in this lane comes at 6:45; the level 6 spike lands around 7:44. Respect the all-in window until your spike is online.