MacroMind matchup data — real ranked games, not opinions
Karthus vs Samira
In ADC, Karthus wins 61% against Samira across 121 observed ranked games. This is an observed win rate shown with its sample size, not a prediction or a guaranteed counter.
By 15 minutes the median game has Karthus behind by 342 gold.
Does Karthus counter Samira?
Yes by the numbers. Karthus wins 61% of 121 ranked ADC games into Samira, and the gap clears the noise band on this sample.
How to beat Samira as Karthus
Turn the early game into gold: 300 up at 10:00 runs this matchup at 77% over 52 games; 300 behind drops it to 49% over 69.
The median first death in this lane comes at 3:38; the level 6 spike lands around 7:17. Respect the all-in window until your spike is online.