MacroMind matchup data: real ranked games, not opinions
Cassiopeia vs Syndra
Cassiopeia vs Syndra in Mid: who wins more often?
Across 645 ranked games in Mid, Cassiopeia beats Syndra in 44% of them.
Global ranked sample: games from every region and every rank pooled together, not one server's stats. Data runs through patch 26.12; curves updated 2026-08-07.
By 15 minutes the median game has Cassiopeia behind by 396 gold.
Cassiopeia at 15:00
- Gold: -396
- CS: -6
- XP: -264
Typical gap to Syndra, from 641 games that reached 15:00.
Does Cassiopeia counter Syndra?
Not this time. Syndra wins 56% of the 645 ranked Mid games counted here. Cassiopeia players still take it back in the right spots, and the rows below show which ones are worth playing for in lane, so pick your fights around them instead of trading even.
Your Cassiopeia game plan against Syndra
With a gold lead at 10:00, Cassiopeia wins 57% of 287 games in this matchup. Behind at the same mark, the rate drops to 34% over 358.
| The spot | Win rate | Games |
|---|---|---|
| Ahead in gold at 10:00 | 57% | 287 |
| Behind in gold at 10:00 | 34% | 358 |
| First blood | 53% | 329 |
| +kills at 10:00 | 56% | 274 |
| +CS at 10:00 | 50% | 287 |
| 0 deaths at 10:00 | 52% | 172 |
| 0 deaths at 15:00 | 64% | 66 |
In the median game here, the first death comes near 6:35 and level 6 lands around 5:26. Until your spike is online, treat the all-in window with respect.
Cassiopeia in Mid: the items that actually get built
Into Syndra specifically, Cassiopeia finishes Rod of Ages first most often: 42.1% over 190 games of this matchup.
The most-finished core in this exact matchup is Rod of Ages, Archangel's Staff, Rylai's Crystal Scepter: 48.6% across 72 games.
The most-finished Cassiopeia core is Rod of Ages, Archangel's Staff, Rylai's Crystal Scepter: 54.2% across 2,129 games when all three got done. All matchups, patches 26.1-26.12.
Most games start Doran's Ring + Health Potion + Health Potion; the first finished item is usually Rod of Ages (5,513 games).
Skill plan: Cassiopeia players max E first and take E at level 1.