MacroMind matchup data — real ranked games, not opinions
Cassiopeia vs Lissandra
Cassiopeia vs Lissandra in Mid: who wins more often?
Across 337 ranked games in Mid, Cassiopeia beats Lissandra in 51% of them. Observed from real matches — the sample size sits next to the rate, here and on every number below.
By 15 minutes the median game has Cassiopeia ahead by 239 gold.
Does Cassiopeia counter Lissandra?
No counter call here: Cassiopeia lands at 51% over 337 games, inside the noise band for a sample this size. Neither pick wins the lane on its own — the swing lives in the spots below, so take the side you play better and use the receipts.
Your Cassiopeia game plan against Lissandra
With a 300-gold lead at 10:00, Cassiopeia wins 55% of 218 games in this matchup. Down 300 at the same mark, the rate drops to 45% over 118.
| The spot | Win rate | Games |
|---|---|---|
| 300 gold up at 10:00 | 55% | 218 |
| 300 gold down at 10:00 | 45% | 118 |
| First blood | 53% | 202 |
| +kills at 10:00 | 59% | 172 |
| +CS at 10:00 | 55% | 226 |
| 0 deaths at 10:00 | 68% | 63 |
In the median game here, the first death comes near 5:07 and level 6 lands around 5:19. Until your spike is online, treat the all-in window with respect.
Cassiopeia in Mid: the items that actually get built
Into Lissandra specifically, Cassiopeia finishes Rod of Ages first most often: 54.2% over 118 games of this matchup.
The most-finished core in this exact matchup is Rod of Ages, Archangel's Staff, Rylai's Crystal Scepter: 61.4% across 44 games.
The most-finished Cassiopeia core is Rod of Ages, Archangel's Staff, Rylai's Crystal Scepter: 54.2% across 2,129 games when all three got done. All matchups, patches 16.1-16.12.
Most games start Doran's Ring + Health Potion + Health Potion; the first finished item is usually Rod of Ages (5,513 games).
Skill plan: Cassiopeia players max E first and take E at level 1.