MacroMind matchup data: real ranked games, not opinions
Cassiopeia vs Lissandra
Cassiopeia vs Lissandra in Mid: who wins more often?
Across 337 ranked games in Mid, Cassiopeia beats Lissandra in 51% of them.
Global ranked sample: games from every region and every rank pooled together, not one server's stats. Data runs through patch 26.12; curves updated 2026-08-07.
By 15 minutes the median game has Cassiopeia ahead by 239 gold.
Cassiopeia at 15:00
- Gold: +239
- CS: +7
- XP: +57
Typical gap to Lissandra, from 334 games that reached 15:00.
Does Cassiopeia counter Lissandra?
Even on the count: Cassiopeia lands at 51% over 337 games. Neither pick wins the lane alone, so take the side you play better and use the rows below to see which early spots swing this one, then play your first ten minutes around them.
Your Cassiopeia game plan against Lissandra
With a gold lead at 10:00, Cassiopeia wins 55% of 218 games in this matchup. Behind at the same mark, the rate drops to 45% over 118.
| The spot | Win rate | Games |
|---|---|---|
| Ahead in gold at 10:00 | 55% | 218 |
| Behind in gold at 10:00 | 45% | 118 |
| First blood | 53% | 202 |
| +kills at 10:00 | 59% | 172 |
| +CS at 10:00 | 55% | 226 |
| 0 deaths at 10:00 | 68% | 63 |
In the median game here, the first death comes near 5:07 and level 6 lands around 5:19. Until your spike is online, treat the all-in window with respect.
Cassiopeia in Mid: the items that actually get built
Into Lissandra specifically, Cassiopeia finishes Rod of Ages first most often: 54.2% over 118 games of this matchup.
The most-finished core in this exact matchup is Rod of Ages, Archangel's Staff, Rylai's Crystal Scepter: 61.4% across 44 games.
The most-finished Cassiopeia core is Rod of Ages, Archangel's Staff, Rylai's Crystal Scepter: 54.2% across 2,129 games when all three got done. All matchups, patches 26.1-26.12.
Most games start Doran's Ring + Health Potion + Health Potion; the first finished item is usually Rod of Ages (5,513 games).
Skill plan: Cassiopeia players max E first and take E at level 1.