MacroMind matchup data: real ranked games, not opinions
Annie vs Syndra
Annie vs Syndra in Mid: who wins more often?
Across 969 ranked games in Mid, Annie beats Syndra in 51% of them.
Global ranked sample: games from every region and every rank pooled together, not one server's stats. Data runs through patch 26.12; curves updated 2026-08-07.
By 15 minutes the median game has Annie behind by 573 gold.
Annie at 15:00
- Gold: -573
- CS: -13
- XP: -453
Typical gap to Syndra, from 964 games that reached 15:00.
Does Annie counter Syndra?
Even on the count: Annie lands at 51% over 969 games. Neither pick wins the lane alone, so take the side you play better and use the rows below to see which early spots swing this one, then play your first ten minutes around them.
Your Annie game plan against Syndra
With a gold lead at 10:00, Annie wins 64% of 336 games in this matchup. Behind at the same mark, the rate drops to 45% over 632.
| The spot | Win rate | Games |
|---|---|---|
| Ahead in gold at 10:00 | 64% | 336 |
| Behind in gold at 10:00 | 45% | 632 |
| First blood | 57% | 459 |
| +kills at 10:00 | 60% | 348 |
| +CS at 10:00 | 60% | 260 |
| 0 deaths at 10:00 | 59% | 255 |
| 0 deaths at 15:00 | 69% | 97 |
In the median game here, the first death comes near 6:37 and level 6 lands around 5:27. Until your spike is online, treat the all-in window with respect.
Annie in Mid: the items that actually get built
Into Syndra specifically, Annie finishes Malignance first most often: 51.5% over 363 games of this matchup.
The most-finished core in this exact matchup is Malignance, Stormsurge, Shadowflame: 64.2% across 53 games.
The most-finished Annie core is Malignance, Stormsurge, Shadowflame: 58.6% across 1,865 games when all three got done. All matchups, patches 26.1-26.12.
Most games start Doran's Ring + Health Potion + Health Potion; the first finished item is usually Malignance (12,521 games).
Skill plan: Annie players max Q first and take Q at level 1.